Diphenhydramine Hydrochloride CAS 147-24-0
Price range: $ 200 through $ 13 000
Diphenhydramine HCl (CAS 147-24-0) – Premium Antihistamine for Pharma & Research
Pharmaceutical-grade Diphenhydramine Hydrochloride – the gold standard antihistamine with proven efficacy in allergy relief and sleep aid formulations. This versatile API offers:
✔ 99%+ purity verified by HPLC
✔ Dual H1 antagonist & anticholinergic action
✔ Ideal for oral, topical & injectable formulations
✔ Batch-specific COA provided
Perfect for:
• OTC allergy/sleep medications
• Motion sickness prevention
• Neuropharmacology research
Available in research to bulk quantities with GMP compliance. Stable white powder, soluble in water/alcohol.
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Diphenhydramine Hydrochloride (CAS 147-24-0) – High-Purity Antihistamine for Pharmaceutical and Research Applications
Premium-Quality First-Generation Antihistamine
Diphenhydramine Hydrochloride (CAS 147-24-0) is a well-established ethanolamine-class antihistamine with proven efficacy in allergy relief, sleep aid formulations, and motion sickness prevention. This pharmaceutical-grade compound meets stringent quality standards, making it ideal for drug development, clinical research, and therapeutic applications.
Key Features & Benefits
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≥99% Pharmaceutical-Grade Purity – Rigorously tested via HPLC, GC-MS, and NMR for batch-to-batch consistency
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Dual-Action Compound – Functions as both a histamine H1 receptor antagonist and anticholinergic agent
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Versatile Therapeutic Effects – Provides antiallergic, antiemetic, sedative, and local anesthetic properties
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Excellent Stability – Long shelf life when stored properly in controlled conditions
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Multiple Application Formats – Suitable for oral, topical, and injectable formulations
Primary Applications
Pharmaceutical Uses
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Allergy Medications: Active ingredient in OTC antihistamines for hay fever and urticaria
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Sleep Aids: Common component in nighttime sleep formulations
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Antiemetics: Used to prevent nausea and motion sickness
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Topical Preparations: Found in anti-itch creams and lotions
Research Applications
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Neuropharmacology Studies: Investigation of histaminergic and cholinergic systems
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Drug Interaction Research: Studying effects with CNS depressants
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Formulation Development: Testing new delivery systems for antihistamines
Technical Specifications
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Chemical Name: 2-(Diphenylmethoxy)-N,N-dimethylethylamine hydrochloride
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Molecular Formula: C₁₇H₂₁NO·HCl
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Molecular Weight: 291.82 g/mol
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Appearance: White crystalline powder
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Solubility: Freely soluble in water and alcohol
Safety & Handling
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Storage Conditions: 15-30°C in airtight, light-resistant containers
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Stability: Stable under recommended storage conditions
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Handling Precautions: Use appropriate PPE (gloves, mask, eye protection)
Quality Assurance
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GMP-Compliant Manufacturing
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Comprehensive Analytical Documentation
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Batch-Specific Certificate of Analysis
Available Forms & Packaging
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Research Quantities: 1g, 5g, 10g, 25g
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Bulk Quantities: 100g, 500g, 1kg+
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Custom Formulations: Available upon request
Why Choose Our Diphenhydramine HCl?
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Consistent High Quality: Manufactured under strict cGMP guidelines
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Technical Support: Expert assistance for your formulation needs
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Global Distribution: Reliable shipping to research and pharmaceutical facilities worldwide
Order Today for Your Pharmaceutical or Research Needs
Contact our sales team for pricing, bulk discounts, and custom synthesis options.
Delivery and Shipping
We offer Express delivery for all products. We are able to provide 3 days delivery for USA, UK , Netherlands, Sweden, Germany, France, New Zealand, Australia and Canada.
Discreet Delivery
We fully understand the need for privacy and security thus your order will be packaged discreetly, vacuum packed and bubble wrapped to ensure safety and integrity where required.
International Shipping
We offer international shipping worldwide, however there are some countries with different laws and regulations on the importation and distribution of our products. Consequently, we have certain shipping restrictions on a number of products that we know to be illegal in the country in which the restriction is in place.
As we are not legal specialists we insist for all customers to check the legality of the product before placing any order. If by any chance your order does not arrive within 21 business days you will qualify for 1 free reship.
We ship all orders using discreet plain packaging along with tracking numbers. Our packages require a supplied signature upon arrival of the shipment and are track-able in detail to the delivery address.
For wholesale orders shipping is free of charge.
We use mostly USPS, FedEx, DHL, Royal Mail, Post NL or EMS services for the shipment of your order. Wholesale orders can take 3 – 6 days depending on country. Please note these times are not guaranteed by us.
Can I track my order?
Yes, you can! After placing your order you will receive an order confirmation via email. Each order starts production 24 hours after your order is placed. Within 72 hours of you placing your order, you will receive an expected delivery date. When the order ships, you will receive another email with the tracking number and a link to trace the order online with the carrier.
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